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Dasatinib

简要描述:Dasatinib
Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family.

  • 产品型号:型号齐全
  • 厂商性质:代理商
  • 更新时间:2022-11-08
  • 访  问  量:58
详情介绍

Dasatinib

Description: Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. Dasatinib may have therapeutic value in fibrotic diseases characterized by elevated levels of Abl and Src kinases.

Name: Dasatinib
CAS#: 302962-49-8 (free)
Chemical Formula: C22H26ClN7O2S
Exact Mass: 487.1557
Molecular Weight: 488.01
Elemental Analysis: C, 54.15; H, 5.37; Cl, 7.26; N, 20.09; O, 6.56; S, 6.57

Synonym: BMS 354825, Dasatinib, Sprycel

IUPAC/Chemical Name: N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide

InChi Key: ZBNZXTGUTAYRHI-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)

SMILES Code: O=C(NC1=C(Cl)C=CC=C1C)C(S2)=CN=C2NC3=NC(C)=NC(N4CCN(CCO)CC4)=C3

Appearance: A crystalline solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001




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