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首页 > 产品中心 > > Accegen > 人肾小球内皮细胞

人肾小球内皮细胞

简要描述:人肾小球内皮细胞
Renal glomerular endothelial cells (GEC) are a specialized microvascular cell type involved in the regulation of glomerular ultrafiltration.

  • 产品型号:型号齐全
  • 厂商性质:代理商
  • 更新时间:2022-10-28
  • 访  问  量:80
详情介绍

product name:Human Renal Glomerular Endothelial Cells(人肾小球内皮细胞);

cat no:ABC-TC3783;

Size/Quantity:1 vial;

Biosafety Level:1;

Shipping Info:Dry Ice;

Storage:Liquid Nitrogen;

Description:Renal glomerular endothelial cells (GEC) are a specialized microvascular cell type involved in the regulation of glomerular ultrafiltration. They form the inner part of the filtration barrier and are involved in pathophysiological processes in the glomerulum. They constitutively synthesize bio-active molecules, to which this basal activity can be chronically augmented by various inflammatory and thrombotic agents. GEC injury exerts significant influences on the progression and repair process of glomerular disease. When the glomerular lesion is severe, angiogenesis is prevented due to endothelial cell injury, with subsequent sclerosis taking place in the impaired region. These glomerular endothelial cell injuries inevitably affect mesangial and epithelial cells and presumably modify the progression of renal disease by reciprocally interacting with them. Because of difficulties associated with the culture, cloning and propagation, the biological properties of these cells remain largely unknown. HRGEC from AcceGen Research Laboratories are isolated from human kidneys. HRGEC are cryopreserved after purification and shipped with dry ice. Each vial contains >5×10^5 cells in 1 ml volume. HRGEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM), and by the formation of microtublar structure in vitro. HRGEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRGEC are guaranteed to expand beyond 15 population doublings at the conditions specified by AcceGen Research Laboratories.;

Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi;

Application:For research use only.


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