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人直肠平滑肌细胞

简要描述:人直肠平滑肌细胞
Smooth muscle contraction is the fundamental event in gastrointestinal motion.

  • 产品型号:型号齐全
  • 厂商性质:代理商
  • 更新时间:2022-10-28
  • 访  问  量:64
详情介绍

product name:Human Rectal Smooth Muscle Cells(人直肠平滑肌细胞);

cat no:ABC-TC3780;

Size/Quantity:1 vial;

Biosafety Level:1;

Shipping Info:Dry Ice;

Storage:Liquid Nitrogen;

Description:Smooth muscle contraction is the fundamental event in gastrointestinal motion. Inflammation of the human intestine causes thickening of the smooth muscle layers which results from the increases in the smooth muscle-specific actins. The increased smooth muscle actins may affect force production and further demonstrate the plasticity of smooth muscle in the inflamed intestine. Human intestinal smooth muscle cells respond to IL-1-beta and TNF-alpha stimulation by releasing IL-6, which might significantly contribute to the overall systemic inflammatory response. Knowledge of molecular mechanism that underlies the control of colorectal smooth muscle tone is essential to advance of understanding of pathophysiology of the abnormality. The availability of human rectal smooth muscle cells in culture will considerably enhance our ability to study the contractile, proliferative and connective tissue responses of the smooth muscle of the human colorectal disorders.HRSMC from AcceGen Research Laboratories are isolated from the human rectum. HRSMC are cryopreserved at primary or passage one culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HRSMC are characterized by immunofluorescent method with antibodies to Α

-smooth muscle actin and desmin. HRSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRSMC are guaranteed to further expand for 15 population doublings in the condition provided by AcceGen Research Laboratories.;

Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi;

Application:For research use only.


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